It is not only the cat that did it: How to prevent and treat congenital toxoplasmosis

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It is not only the cat that did it: how to prevent and treat congenital toxoplasmosis.

The apicomplexan parasite Toxoplasma gondii was discovered a little over one hundred years ago and was soon recognized as a pathogen responsible for congenital infection. But detailed understanding of its epidemiology emerged only after 1970 with the discovery of its life cycle. In the last ten years, high resolution molecular tools have allowed the characterization of various strain types with...

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Why prevent, diagnose and treat congenital toxoplasmosis?

Evidence that prevention, diagnosis and treatment of toxoplasmosis is beneficial developed as follows: anti-parasitic agents abrogate Toxoplasma gondii tachyzoite growth, preventing destruction of infected, cultured, mammalian cells and cure active infections in experimental animals, including primates. They treat active infections in persons who are immune-compromised, limit destruction of ret...

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ژورنال

عنوان ژورنال: Journal of Infection

سال: 2014

ISSN: 0163-4453

DOI: 10.1016/j.jinf.2013.09.023